Vitamin B5
TYPE OF INGREDIENT
Humectant, enzymatic cofactor, anti-inflammatory
COMMONLY FOUND IN
Serums, moisturizers, masks
WHAT ARE THE BENEFITS OF VITAMIN B5?
Vitamin B5 is involved in multiple integumentary processes, including fibroblast proliferation in wounding. Additionally, it has beneficial moisturizer effects on the skin; its absence has shown reduced keratinocyte proliferation and differentiation, implying its unique role in this process. It has more recently been shown to inhibit growth of certain bacterial organisms. Clinically, it has been used to treat facial redness in combination with other agents.
WHAT IS VITAMIN B5?
Vitamin B5 (Pantothenic acid) is the source of coenzyme A, a cofactor for multiple cellular processes. It is a water-soluble vitamin, and its presence is essential in wound healing.
IS VITAMIN B5 SAFE FOR ALL SKIN TYPES AND TONES?
Based on available evidence, vitamin B5 is safe for all skin types and tones.
CONTRAINDICATIONS
Although there are likely no major contraindications for the topical application of vitamin B5, it should be used with caution in patients with an allergy to it or its derivatives.
Sources:
Chohnan S, Murase M, Kurikawa K, Higashi K, Ogata Y. Antimicrobial activity of pantothenol against staphylococci possessing a prokaryotic type II pantothenate kinase. Microbes Environ. 2014;29(2):224-226.
Kobayashi D, Kusama M, Onda M, Nakahata N. The Effect of Pantothenic Acid Deficiency on Keratinocyte Proliferation and the Synthesis of Keratinocyte Growth Factor and Collagen in Fibroblasts. J Pharmacol Sci. 2011;115(2):230-234.
Nisbet SJ, Targett D, Rawlings AV, et al. Clinical and in vitro evaluation of new anti-redness cosmetic products in subjects with winter xerosis and sensitive skin. Int J Cosmet Sci. 2019;41(6):534-547.
