RESORCINOL

TYPE OF INGREDIENT​
Antiseptic, exfoliating agent
COMMONLY FOUND IN
Hair dyes, chemical peels, acne treatments, skin-lightening products

WHAT ARE THE BENEFITS OF RESORCINOL?

Resorcinol is a versatile phenolic compound widely used in various personal care products. Its primary applications include:

  • Hair Dye: Resorcinol is a key ingredient in permanent hair dyes, contributing to the color-forming process by reacting with other chemicals to produce a range of colors.
  • Acne Treatment: Due to its antibacterial properties, resorcinol is effective in treating acne and other skin conditions by reducing bacteria and exfoliating dead skin cells. Resorcinol is a component of Jessner’s Peel, a common facial peel solution that can help treat acne, hyperpigmentation and other conditions. 
  • Hidradenitis Suppurativa: Resorcinol can help reduce symptoms and the number of hidradenitis lesions, leading to quality-of-life improvements that rival topical antibiotics.
  • Skin Lightening: Resorcinol can help in lightening skin pigmentation, making it useful in products targeting hyperpigmentation and melasma.

WHAT IS RESORCINOL?

Resorcinol, a dihydroxy benzene, is a chemical compound used extensively in cosmetic and pharmaceutical products. It is known for its antiseptic and exfoliating properties, making it beneficial for treating various skin conditions. 

IS RESORCINOL SAFE FOR ALL SKIN TYPES AND TONES?

While resorcinol is effective, it is also a potent chemical that can cause skin irritation and sensitization in some individuals. It is important to use products containing resorcinol as directed and perform a patch test before full application. Those with sensitive skin or allergies should consult with a dermatologist prior to use.

CONTRAINDICATIONS

Allergic Reactions: Resorcinol can cause allergic reactions in some individuals, leading to symptoms such as redness, itching and swelling. Individuals with suspected contact dermatitis from hair dye may consider patch testing to rule out resorcinol allergy.

Skin Irritation: Individuals with extremely sensitive skin should test a small amount of resorcinol on the skin prior to applying it on a wide surface area. If using other potent active ingredients (like retinoids or strong acids), it is advisable to consult with a dermatologist to avoid potential skin irritation or adverse interactions. Overuse or improper use of resorcinol can lead to irritant contact dermatitis and skin irritation. 

Pregnant or Breastfeeding: Individuals who are pregnant or breastfeeding should avoid products containing resorcinol due to potential risks and limited safety data.

Sources:

Cordero-Ramos J, Barros-Tornay R, Toledo-Pastrana T, Ferrándiz L, Calleja-Hernández MÁ, Moreno-Ramírez D. Effectiveness and safety of topical 15% resorcinol in the management of mild-to-moderate hidradenitis suppurativa: A cohort study. J Dermatol. 2022 Apr;49(4):459-462. 

Katoulis A, Efthymiou O, Liakou A, Pappa G, Kanelleas A, Koumaki D, Bozi E, Sgouros D. Resorcinol 10% as a Promising Therapeutic Option for Mild Hidradenitis Suppurativa: A Prospective, Randomized, Open Study. Skin Appendage Disord. 2023 Dec;9(6):438-443. 

Huh SY, Shin JW, Na JI, Huh CH, Youn SW, Park KC. The Efficacy and Safety of 4-n-butylresorcinol 0.1% Cream for the Treatment of Melasma: A Randomized Controlled Split-face Trial. Ann Dermatol. 2010 Feb;22(1):21-5. 

Bae BG, Park CO, Shin H, Lee SH, Lee YS, Lee SJ, Chung KY, Lee KH, Lee JH. Salicylic acid peels versus Jessner’s solution for acne vulgaris: a comparative study. Dermatol Surg. 2013 Feb;39(2):248-53. 

Aamir Hussain, MD, MAPP

Author

Dr. Aamir Hussain is a dermatologist currently practicing adult and pediatric dermatology in Northern Virginia. He serves on the health policy committee of the American Contact Dermatitis Society and has a clinical interest in patch testing. Dr. Hussain is an internationally-recognized speaker, writer and educator. His writings on health policy, medical education and the connections between healthcare and faith have been featured in prestigious media outlets, including The New York Times, The Washington Post, The Hill, and The Baltimore Sun. He has published numerous articles in peer-reviewed journals and is the author of several book chapters. He has presented research at major conferences, including the American Academy of Dermatology, World Congress of Dermatology, Society of Pediatric Dermatology, American Contact Dermatitis Society, American Society of Dermatopathology, Society of Investigative Dermatology and the American Society for Dermatologic Surgery.