Due to its larger molecular size, mandelic acid penetrates the skin more slowly, making it a gentler alternative to alpha hydroxy acids (AHAs) and less likely to cause irritation. This makes it suitable for sensitive skin. Mandelic acid exfoliates by removing dead skin cells, promoting smoother and more even-toned skin. Its antibacterial properties help unclog pores, which is beneficial for acne-prone skin. It also inhibits tyrosinase, reducing dark spots, and stimulates collagen to reduce fine lines and wrinkles, making it useful for anti-aging.
Mandelic acid is a water-soluble alpha hydroxy acid (AHA) derived from bitter almonds.
Mandelic acid is safe for all skin tones and has a low risk of post-inflammatory hyperpigmentation. It is also well tolerated by sensitive and acne-prone skin due to its gentle exfoliating properties.
While there are no specific contraindications, mandelic acid can increase sun sensitivity and so sunscreen is imperative to use in conjunction. Additionally, individuals with almond allergies should patch test before use to ensure safety.
Jacobs SW, Culbertson EJ. Effects of Topical Mandelic Acid Treatment on Facial Skin Viscoelasticity. Facial Plast Surg. 2018 Dec;34(6):651-656. doi: 10.1055/s-0038-1676048. Epub 2018 Dec 4. PMID: 30513536.