CURCUMIN
TYPE OF INGREDIENT
Antioxidant, anti-inflammatory
COMMONLY FOUND IN
Facial oils, serums
WHAT ARE THE BENEFITS OF CURCUMIN ?
Curcumin has been used in many dermatologic conditions, including lichen planus, psoriasis, vitiligo, basal cell carcinoma (via upregulation of p53), squamous cell carcinoma (via NF-kappa-beta inhibition) and cutaneous T-cell lymphoma (by downregulating STAT-3). In animal studies it accelerates wound healing based on its antioxidant activity. It may also have antimicrobial effects against Candida.
WHAT IS CURCUMIN ?
Curcumin is the most biologically active component in turmeric (Curcuma longa). Its health benefits have been explored due to its antioxidant, anti-inflammatory, antineoplastic and antimicrobial effects.
IS CURCUMIN SAFE FOR ALL SKIN TYPES AND TONES?
Curcumin is likely safe for all skin types and tones based on available evidence. Allergic contact dermatitis and pigmented contact dermatitis has been observed with it.
CONTRAINDICATIONS
There are many adverse effects of curcumin that have been observed, typically in high concentrations when taken orally. These effects include diarrhea and nausea, which are the most common. It is contraindicated for biliary obstruction, gallstones and hypersensitivity reactions.
Sources
Alshaikh AA, Bharti RK. Spontaneous Reversal of Vitiligo, a Rare Phenomenon Reported in a Case in Saudi Arabia with an Insight into Metabolic Biochemical Derangements. Medicina (Kaunas). 2023;59(3):427. Published 2023 Feb 22.
Bhaskar Rao A, Prasad E, Deepthi SS, et al. Wound healing: a new perspective on glucosylated tetrahydrocurcumin. Drug Des Devel Ther. 2015;9:3579-3588. Published 2015 Jul 13.
Ghasemi H, Saxtrup K, Al-Khafagi AAM, Thorup B, Sommerlund M. Ugeskr Laeger. 2018;180(42):V06180419.
Gopinath H, Karthikeyan K. Turmeric: A condiment, cosmetic and cure. Indian J Dermatol Venereol Leprol. 2018;84(1):16-21.
Jeon HJ, Kim K, Kim C, Lee SE. Antimelanogenic Effects of Curcumin and Its Dimethoxy Derivatives: Mechanistic Investigation Using B16F10 Melanoma Cells and Zebrafish (Danio rerio) Embryos. Foods. 2023;12(5):926. Published 2023 Feb 22.
Liu X, Zhang R, Shi H, et al. Protective effect of curcumin against ultraviolet A irradiation‑induced photoaging in human dermal fibroblasts. Mol Med Rep. 2018;17(5):7227-7237.
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