Bisoctrizole is a broad-spectrum ultraviolet light filter, protecting the skin from harmful ultraviolet rays in the UVA1, UVA2 and UVB ranges.
Bisoctrizole (i.e., methylene bis-benzotriazolyl tetramethylbutylphenol) is an organic, scattering ultraviolet (UV) light filter that covers the UVA1, UVA2 and UVB spectrum. It is approved in the European Union as of 2000.
In vivo studies showed no potential for contact dermatitis, photoallergy or phototoxicity. Thus, based on the available evidence, it is likely safe for all skin types and tones.
Minimal percutaneous absorption has been observed, so individuals with hypersensitivity should avoid the product. There have been reports of patch testing positivity to the product.
Gonzalez ME, Soter NA, Cohen DE. Positive patch- and photopatch-test reactions to methylene bis-benzotriazolyl tetramethylbutylphenol in patients with both atopic dermatitis and chronic actinic dermatitis. Dermatitis. 2011;22(2):106-111.
Pantelic MN, Wong N, Kwa M, Lim HW. Ultraviolet filters in the United States and European Union: A review of safety and implications for the future of US sunscreens. J Am Acad Dermatol. 2023;88(3):632-646.
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