Baicalin

TYPE OF INGREDIENT​
Antioxidant, anti-aging
COMMONLY FOUND IN
Serums

WHAT ARE THE BENEFITS OF BAICALIN?

When added to products, baicalin provides additional antioxidant and anti-aging effects to improve skin quality and appearance. Additionally, it has been shown to reduce UVB-related pyrimidine dimer production and UVA-related photoaging.

WHAT IS BAICALIN?

Baicalin is from the root of the Chinese skullcap and is often used in East Asia. It contains flavonoids with antioxidant properties. Baicalin has been shown to be a free radical scavenger.

IS BAICALIN SAFE FOR ALL SKIN TYPES AND TONES?

Baicalin is likely safe for all skin types and tones based on available data. However, patients with known hypersensitivity to baicalin or its derivatives should be cautious with use.

CONTRAINDICATIONS

There is minimal data on contraindications for the topical application of baicalin.

Sources:

Farris P, Yatskayer M, Chen N, Krol Y, Oresajo C. Evaluation of efficacy and tolerance of a nighttime topical antioxidant containing resveratrol, baicalin, and vitamin e for treatment of mild to moderately photodamaged skin. J Drugs Dermatol. 2014;13(12):1467-1472.

Qiao Y, Dong H, Zhang X. A Versatile Sunscreen with Minimal ROS Damage and Low Permeability. ACS Appl Mater Interfaces. 2020;12(5):6217-6225.

Zhou BR, Luo D, Wei FD, Chen XE, Gao J. Baicalin protects human fibroblasts against ultraviolet B-induced cyclobutane pyrimidine dimers formation. Arch Dermatol Res. 2008;300(6):331-334.

Nishad Sathe, MD

Author

Nishad Sathe is a PGY-3 Internal Medicine/Dermatology resident at the University of Minnesota