Cinoxate
TYPE OF INGREDIENT
Ultraviolet filter
COMMONLY FOUND IN
Sunscreens, creams, cosmetic products
What are the benefits of cinoxate?
Like other chemical agents, cinoxate provides protection against the ultraviolet-B (UV-B) range of light.
WHAT IS CINOXATE ?
Cinoxate (i.e., 2-ethoxyethyl p-methoxycinnamate) is a water-insoluble ultraviolet-B (UV-B) light filter used in sunscreens and cosmetic products.
IS CINOXATE SAFE FOR ALL SKIN TYPES AND TONES?
Cinoxate is safe for all skin types and tones based on available literature; however, there are multiple case reports of photoallergic contact dermatitis related to products containing cinoxate. Therefore, this product should be used with caution in patients though it is rarely used in most cosmetic formulations.
___ CONTRAINDICATIONS
Cinoxate products should be avoided in patients who have a prior history of allergy to products containing it. Despite approval by the FDA, cinoxate is seldom encountered in skin products in the United States.
Sources:
Davies MG, Hawk JL, Rycroft RJ. Acute photosensitivity from the sunscreen 2-ethoxyethyl-p-methoxycinnamate. Contact Dermatitis. 1982;8(3):190-192.
Gunia-Krzyżak A, Słoczyńska K, Popiół J, Koczurkiewicz P, Marona H, Pękala E. Cinnamic acid derivatives in cosmetics: current use and future prospects. Int J Cosmet Sci. 2018;40(4):356-366.
Murphy GM, White IR. Photoallergic contact dermatitis to 2-ethoxyethyl-p-methoxycinnamate. Contact Dermatitis. 1987;16(5):296.
Pantelic MN, Wong N, Kwa M, Lim HW. Ultraviolet filters in the United States and European Union: A review of safety and implications for the future of US sunscreens. J Am Acad Dermatol. 2023;88(3):632-646.
